400-885-9898
职位描述
生物研发
About BeiGene and BeiGene Institute
Over the past decade BeiGene has grown exponentially and become an industry leader with a robust drug pipeline combined with strong production capacity. In addition, as an emerging industry leader with over 7000 employees globally, BeiGene has built a world-class clinical development team and a leading commercial team to bring accessible and affordable medicines to patients around the world.
As part of its ongoing efforts to drive the development of truly innovative and transformative medicines, BeiGene is creating a brand-new research institution in Shanghai, China, BeiGene Institute. Our goal is to establish a cross-disciplinary research organization where cutting-edge science and technology drive the discovery of impactful Insights into human health and disease. BeiGene Institute functions as an independent research entity within BeiGene to enable sustainable scientific discoveries and innovation.
Why BeiGene Institute
BeiGene Institute is a diverse and inclusive community where scientists will bring their expertise, creativity, and originality to a group of dynamic colleagues and collaborators.
BeiGene Institute is structured with groups with specific research focuses. Individual group head leads a team staffed with postdocs and research associates. You will have a unique opportunity for career development in an environment that crosses between industry and academia.
Scientists will have access to state-of-the-art technologies to perform ground-breaking work to address fundamental biology and technology questions. We are well-supported to carry out independent research and pursue collaborations within and beyond BeiGene.
Besides being encouraged to publish their research work, we are empowered to explore the translational potential of our own scientific discoveries and play an active role in our collective effort of discovering drug candidates and establishing biomarkers across major diseases, including cancer and inflammatory diseases.
We offer a highly competitive compensation package, and rank and salary commensurate with qualifications.
We are seeking independent and creative Research Investigators to join Dr. Ling Wu’s group.
Dr. Ling Wu recently joined BeiGene as a Principle Investigator and Associate Research Chief of BeiGene Institute. He has extensive experience in innovative biotechnology development spanning over 10 years, holding many patents to his name and acting as scientific co-founder of a biotech startup built upon his discoveries. His works have been published in many impactful journals, including Cell Rep Medicine, Cellular & Molecular Immunology, and Journal of Controlled Release. Dr. Wu’s current interests span the basic and translational spectrum of understanding ways to combat cancer by immune engineering, e.g. CAR/TCR-T immunotherapy. Dr. Wu completed his Ph.D study and post-doctoral training in a world renowned immunology lab at the National University of Singapore. Prior to that, he finished his Bs and Ms in Peking University and as a visiting scholar in Harvard medical school, with a study focus on biopharmaceutical protein engineering.
Main research focuses of Dr. Ling Wu’s group are:
High-throughput novel gene discovery and gene edited T cell immunotherapy
Off-the-shelf CAR/TCR-T
Tumor and immunity interactions
Multidisciplinary and computational methods of novel cancer target and receptor discovery
Job responsibilities
The successful candidates will
Initiate and conduct research projects independently
Collaborate with other group members to drive innovation and productivity
Mentor and support junior staff members
Over the past decade BeiGene has grown exponentially and become an industry leader with a robust drug pipeline combined with strong production capacity. In addition, as an emerging industry leader with over 7000 employees globally, BeiGene has built a world-class clinical development team and a leading commercial team to bring accessible and affordable medicines to patients around the world.
As part of its ongoing efforts to drive the development of truly innovative and transformative medicines, BeiGene is creating a brand-new research institution in Shanghai, China, BeiGene Institute. Our goal is to establish a cross-disciplinary research organization where cutting-edge science and technology drive the discovery of impactful Insights into human health and disease. BeiGene Institute functions as an independent research entity within BeiGene to enable sustainable scientific discoveries and innovation.
Why BeiGene Institute
BeiGene Institute is a diverse and inclusive community where scientists will bring their expertise, creativity, and originality to a group of dynamic colleagues and collaborators.
BeiGene Institute is structured with groups with specific research focuses. Individual group head leads a team staffed with postdocs and research associates. You will have a unique opportunity for career development in an environment that crosses between industry and academia.
Scientists will have access to state-of-the-art technologies to perform ground-breaking work to address fundamental biology and technology questions. We are well-supported to carry out independent research and pursue collaborations within and beyond BeiGene.
Besides being encouraged to publish their research work, we are empowered to explore the translational potential of our own scientific discoveries and play an active role in our collective effort of discovering drug candidates and establishing biomarkers across major diseases, including cancer and inflammatory diseases.
We offer a highly competitive compensation package, and rank and salary commensurate with qualifications.
We are seeking independent and creative Research Investigators to join Dr. Ling Wu’s group.
Dr. Ling Wu recently joined BeiGene as a Principle Investigator and Associate Research Chief of BeiGene Institute. He has extensive experience in innovative biotechnology development spanning over 10 years, holding many patents to his name and acting as scientific co-founder of a biotech startup built upon his discoveries. His works have been published in many impactful journals, including Cell Rep Medicine, Cellular & Molecular Immunology, and Journal of Controlled Release. Dr. Wu’s current interests span the basic and translational spectrum of understanding ways to combat cancer by immune engineering, e.g. CAR/TCR-T immunotherapy. Dr. Wu completed his Ph.D study and post-doctoral training in a world renowned immunology lab at the National University of Singapore. Prior to that, he finished his Bs and Ms in Peking University and as a visiting scholar in Harvard medical school, with a study focus on biopharmaceutical protein engineering.
Main research focuses of Dr. Ling Wu’s group are:
High-throughput novel gene discovery and gene edited T cell immunotherapy
Off-the-shelf CAR/TCR-T
Tumor and immunity interactions
Multidisciplinary and computational methods of novel cancer target and receptor discovery
Job responsibilities
The successful candidates will
Initiate and conduct research projects independently
Collaborate with other group members to drive innovation and productivity
Mentor and support junior staff members
Requirements:
The success applicants will have a Master degree in 2023 or earlier.
The applicants should have a solid background and significant experience in one or more of the following areas:
molecular biology, immunology, cancer biology, stem cell biology
A solid record of scientific accomplishment
Ability to independently design and execute experiments, interpret data, and identify appropriate follow-up strategies
Ability to collaborate in a dynamic environment
Specialized skills: (key skills are highlighted)
Molecular Biology: Molecular Cloning and Vector Designation (Adenovirus, Lentivirus), DNA library construction, siRNA and shRNA knockdown, CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 Knock-out and Knock-in, Eptopic expression, qPCR, PAGE, Western Blotting, ELISA, Immunohistochemistry, Immunofluorescence, IP(Immunoprecipitation).
Cell Biology: Cell lines culture, Primary cell culture, 3D carcinoma and organoids culture, iPSC differentiation, FACSs and cell sorting, Cell imaging, Cell functions (xCelligence/Incucyte, Seahorse cell respiration).
Animal Research: Animal Care, handling and breeding, drug delivery (IP, SC, Gavage, IV), Survival blood collection, Tumor immune cell isolation, lymphoid organ extraction, mouse models setup (liquid and solid tumor in immune competent or compromised mice).
Big Data Science (Plus): Bulk RNA-seq analysis, ATAC-Seq, ChIP-Seq
The success applicants will have a Master degree in 2023 or earlier.
The applicants should have a solid background and significant experience in one or more of the following areas:
molecular biology, immunology, cancer biology, stem cell biology
A solid record of scientific accomplishment
Ability to independently design and execute experiments, interpret data, and identify appropriate follow-up strategies
Ability to collaborate in a dynamic environment
Specialized skills: (key skills are highlighted)
Molecular Biology: Molecular Cloning and Vector Designation (Adenovirus, Lentivirus), DNA library construction, siRNA and shRNA knockdown, CRISPR (clustered regularly interspaced short palindromic repeats)-Cas9 Knock-out and Knock-in, Eptopic expression, qPCR, PAGE, Western Blotting, ELISA, Immunohistochemistry, Immunofluorescence, IP(Immunoprecipitation).
Cell Biology: Cell lines culture, Primary cell culture, 3D carcinoma and organoids culture, iPSC differentiation, FACSs and cell sorting, Cell imaging, Cell functions (xCelligence/Incucyte, Seahorse cell respiration).
Animal Research: Animal Care, handling and breeding, drug delivery (IP, SC, Gavage, IV), Survival blood collection, Tumor immune cell isolation, lymphoid organ extraction, mouse models setup (liquid and solid tumor in immune competent or compromised mice).
Big Data Science (Plus): Bulk RNA-seq analysis, ATAC-Seq, ChIP-Seq
工作地点
百济神州(上海)医药研发有限公司
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职位发布者
张婧媛/人事经理
刚刚活跃立即沟通
百济神州北京
About BeiGene BeiGene is a publically traded(BGNE, NASDAQ), globally focused biopharmaceutical company dedicated to becoming a leader in the discovery and development of innovative, molecularly targeted and immuno-oncology drugs for the treatment of cancer. Our cancer biology platform addresses the importance of tumor-immune system interactions and the value of primary tumor biopsies in developing new cancer models. We have a global team of over 200 individuals, including over 150 scientists and clinicians, and a world-renowned scientific advisory board, with deep scientific talent, extensive pharmaceutical experience, and a commitment to improving the lives of cancer patients around the world. Our clinical pipeline is comprised of novel oral small molecules and monoclonal antibodies(mAb) for cancer, including an anti-PD-1 monoclonal antibody, a best-in-class BTK inhibitor, a RAF dimer inhibitor, a best-in-class PARP inhibitor, and a variety of combination clinical studies. In addition, our robust preclinical programs are expected to generate more small molecule and mAb drugs for clinical development in coming years. For more information, please visit our website at www.beigene.com.
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